SCHEMBL13023907

SCHEMBL13023907

Cc1cc(C)c(N2c3ccccc3S(=O)(=O)c3c2oc2ccccc32)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 2/20 0.34
PIK3CA P42336 2/20 0.34
PIK3CB P42338 2/20 0.34
PIK3CG P48736 2/20 0.34
LMNA P02545 4/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 2/20 0.33
POLB P06746 1/20 0.33
RXFP1 Q9HBX9 1/20 0.31
MAPK1 P28482 1/20 0.31
TNKS O95271 1/20 0.31
PARP1 P09874 1/20 0.31
MAOB P27338 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
PARP2 Q9UGN5 1/20 0.31
MAOA P21397 1/20 0.31
ALDH1A1 P00352 1/20 0.30
PRKDC P78527 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13022813 0.91 LMNA (0.34) LMNAMAPTSMN1; SMN2TP53POLB
SCHEMBL13023831 0.87 LMNA (0.37) PIK3CDPIK3CAPIK3CBPIK3CGLMNA
SCHEMBL13023898 0.86 MEN1 (0.36) MAPTSMN1; SMN2POLBMAOAALDH1A1
SCHEMBL13022820 0.82 LMNA (0.32) LMNAMAPTSMN1; SMN2TP53POLB
SCHEMBL13022106 0.81 PRKDC (0.35) LMNAMAPTSMN1; SMN2TP53ALDH1A1
SCHEMBL13065776 0.81 LMNA (0.34) LMNAMAPTTP53POLBTNKS
SCHEMBL13023861 0.79 KDM4E (0.34) LMNAMAPTSMN1; SMN2TP53TNKS
SCHEMBL13023848 0.79 POLB (0.40) LMNAMAPTSMN1; SMN2POLBALDH1A1
SCHEMBL13022781 0.79 MAPT (0.36) LMNAMAPTSMN1; SMN2TP53POLB
SCHEMBL13022722 0.78 MAPT (0.39) LMNAMAPTTP53POLBRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 PIK3CD 3316/4885PIK3CA 2273/4885PIK3CB 3549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.