Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.54 |
| ▸ | NPC1 | O15118 | 10/20 | 0.54 |
| ▸ | RAB9A | P51151 | 10/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.54 |
| ▸ | RELA | Q04206 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 11/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.52 |
| ▸ | MEN1 | O00255 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767775 | 0.84 | NPC1 (0.54) | MAPTSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL1506734 | 0.80 | INSR (0.65) | MAPTSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL31314986 | 0.80 | INSR (0.65) | MAPTSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL28555429 | 0.76 | INSR (0.47) | MAPTSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL22331496 | 0.76 | MAPT (0.59) | MAPTSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL11511649 | 0.76 | MAPT (0.49) | MAPTSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL19757181 | 0.75 | SNCA (0.49) | MAPTSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL6655466 | 0.74 | HPGD (0.54) | MAPTSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL28234601 | 0.74 | INSR (0.54) | MAPTSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL3112891 | 0.73 | NPC1 (0.78) | MAPTSMN1; SMN2NPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148647-B1 | HAIR DYE COMPOSITION | KAO CORP (JP) | 2016-04-06 | — | — | EP | disclosed |
| US-7824449-B2 | Hair dye composition | KAO CORPORATION (JP) | 2010-11-02 | — | — | US | disclosed |
| US-7824449-B2 | Hair dye composition | KAO CORPORATION (JP) | 2010-11-02 | — | — | US | disclosed |
| US-20100115710-A1 | HAIR DYE COMPOSITION | KAO CORPORATION (JP) | 2010-05-13 | — | — | US | disclosed |
| US-20100115710-A1 | HAIR DYE COMPOSITION | KAO CORPORATION (JP) | 2010-05-13 | — | — | US | disclosed |
| WO-2008139985-A2 | HAIR DYE COMPOSITION | KAO CORPORATION (JP) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100115710-A1 | HAIR DYE COMPOSITION | SAT1, S100B, NAT1 | MAPT 2862/4885SMN1; SMN2 4246/4885NPC1 2905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.