Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.49 |
| ▸ | HRH2 | P25021 | 4/20 | 0.45 |
| ▸ | HRH1 | P35367 | 4/20 | 0.45 |
| ▸ | YAP1 | P46937 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073844 | 1.00 | GPR119 (0.49) | GPR119HRH2HRH1YAP1ITGB3 | |
| SCHEMBL2895126 | 0.93 | ITGB3 (0.52) | GPR119HRH2HRH1YAP1ITGB3 | |
| SCHEMBL2891888 | 0.93 | ITGB3 (0.52) | GPR119HRH2HRH1YAP1ITGB3 | |
| SCHEMBL2900152 | 0.91 | HRH2 (0.52) | GPR119HRH2HRH1YAP1ITGB3 | |
| SCHEMBL2897695 | 0.90 | HRH2 (0.42) | GPR119HRH2HRH1YAP1ITGB3 | |
| SCHEMBL2898097 | 0.90 | HRH2 (0.42) | GPR119HRH2HRH1YAP1ITGB3 | |
| SCHEMBL2897693 | 0.90 | HRH2 (0.42) | GPR119HRH2HRH1YAP1ITGB3 | |
| SCHEMBL2897812 | 0.89 | GPR119 (0.45) | GPR119HRH2HRH1YAP1GPR183 | |
| SCHEMBL2897810 | 0.89 | GPR119 (0.45) | GPR119HRH2HRH1YAP1GPR183 | |
| SCHEMBL2899006 | 0.89 | GPR119 (0.51) | GPR119GPR183KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286112-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
| US-20100286112-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286112-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | GPR119, DPP4, DPP9 | GPR119 1/4885HRH2 877/4885HRH1 1577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.