SCHEMBL1302811

SCHEMBL1302811

C#Cc1ccccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.48
ALDH1A1 P00352 5/20 0.42
HSD17B10 Q99714 2/20 0.42
HPGD P15428 1/20 0.42
BCL2L1 Q07817 1/20 0.42
MAPK1 P28482 1/20 0.42
ESR2 Q92731 1/20 0.42
GRM5 P41594 1/20 0.40
BACE1 P56817 1/20 0.39
DPP4 P27487 1/20 0.38
FFAR1 O14842 1/20 0.38
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2E1 P05181 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C8 P10632 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6757877 0.95 CYP2A6 (0.44) CYP2A6ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL29159006 0.93 CYP2A6 (0.46) CYP2A6ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL3795851 0.91 CYP2A6 (0.44) CYP2A6ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL30607044 0.85 ESR2 (0.38) CYP2A6ESR2GABRG2GABRB3GABRA5
SCHEMBL29051242 0.85 ESR2 (0.38) CYP2A6ESR2GABRG2GABRB3GABRA5
SCHEMBL6517747 0.84 ESR2 (0.42) CYP2A6ESR2FFAR1CYP1A2CYP2C9
SCHEMBL7932656 0.84 MEN1 (0.33) CYP2A6ALDH1A1MAPK1ESR2CYP1A2
SCHEMBL651587 0.82 ALDH1A1 (0.44) CYP2A6ALDH1A1HPGDMAPK1ESR2
SCHEMBL7932862 0.82 ESR2 (0.41) ALDH1A1HPGDMAPK1ESR2GRM5
SCHEMBL6512088 0.82 ESR2 (0.41) CYP2A6ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114702516-A Red fluorescent material based on BODIPY, preparation method and application thereof 东南大学 2022-07-05 CN claimed
WO-2025106722-A1 INHIBITORS OF STK33, RET, CLK, AND/OR RELATED KINASES AND METHODS USING SAME BAYLOR COLLEGE OF MEDICINE (US) 2025-05-22 WO disclosed
CN-118027090-A Method for generating silanol by oxidizing silane 吉林大学 2024-05-14 CN disclosed
CN-116444547-B Naphthalene boron-nitrogen compound and application thereof 浙江八亿时空先进材料有限公司 2024-02-02 CN disclosed
CN-116891567-A Preparation method and application of alpha-diimine palladium functionalized conjugated organic porous material 泰山学院 2023-10-17 CN disclosed
CN-116444336-A Fused ring compound and application thereof 浙江八亿时空先进材料有限公司 2023-07-18 CN disclosed
CN-116444547-A Naphthalene boron-nitrogen compound and application thereof 浙江八亿时空先进材料有限公司 2023-07-18 CN disclosed
CN-116410475-A Zirconium-based metal-organic framework material, preparation method and application thereof, adsorption separation device and method 中国石油天然气股份有限公司 2023-07-11 CN disclosed
CN-114702516-A Red fluorescent material based on BODIPY, preparation method and application thereof 东南大学 2022-07-05 CN disclosed
CN-110563531-B Synthetic method of 1, 2-disubstituted olefin compound 浙江工业大学 2022-06-21 CN disclosed
WO-1998016503-A2 THE PREPARATION AND USE OF ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS AMERICAN CYANAMID COMPANY (US) 1998-04-23 WO disclosed
US-5276021-A Anticholesterol or antilipemic agents E. R. SQUIBB & SONS, INC. (US) 1994-01-04 US disclosed
US-5091378-A Anticholesterol agents E. R. SQUIBB & SONS, INC. (US) 1992-02-25 US disclosed
US-4536515-A Substituted phenylalkenoic acids and esters MERCK FROSST CANADA, INC. (CA) 1985-08-20 US disclosed
US-4453005-A Process for preparing substituted phenylalkenoic acids MERCK FROSST CANADA, INC. (CA) 1984-06-05 US disclosed
US-4301313-A ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS ELI-LILLY AND COMPANY (US) 1981-11-17 US disclosed
US-4221895-A POLYESTER, POLYSULFONATE, OR POLYSULFINATE THE DOW CHEMICAL COMPANY (US) 1980-09-09 US disclosed
US-4073936-A Hypolipidemic allene carboxylic esters SANDOZ, INC. (US) 1978-02-14 US disclosed
US-4011339-A ANTIINFLAMMATORY AGENTS SANDOZ, INC. (US) 1977-03-08 US disclosed
US-3979468-A ANTIINFLAMMATORY AGENTS ALLEN & HANBURYS LIMITED (EN) 1976-09-07 US disclosed