SCHEMBL6512088

SCHEMBL6512088

C#Cc1ccccc1-c1ccc(I)cc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.41
PTPN5 P54829 1/20 0.33
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6757877 0.83 CYP2A6 (0.44) ESR2CYP2A6
SCHEMBL3951368 0.83 ESR2 (0.44) ESR2PTPN5CYP2A6
SCHEMBL1302811 0.82 CYP2A6 (0.48) ESR2CYP2A6
SCHEMBL6517747 0.81 ESR2 (0.42) ESR2PTPN5CYP2A6
SCHEMBL29159006 0.80 CYP2A6 (0.46) ESR2CYP2A6
SCHEMBL7932862 0.79 ESR2 (0.41) ESR2
SCHEMBL29588993 0.79 CYP3A4 (0.44) ESR2
SCHEMBL651587 0.79 ALDH1A1 (0.44) ESR2PTPN5CYP2A6
SCHEMBL4373221 0.79 ESR2 (0.66) ESR2PTPN5
SCHEMBL27762468 0.79 CYP1A2 (0.44) ESR2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112079856-A 4-iodophenyl substituted carborane derivative and preparation method thereof 盐城工学院 2020-12-15 CN disclosed
US-20050101063-A1 Three-terminal field-controlled molecular devices TOUR JAMES M (US) 2005-05-12 US disclosed
WO-2002035580-A2 THREE-TERMINAL FIELD-CONTROLLED MOLECULAR DEVICES MOLECULAR ELECTRONICS CORPORATION (US) 2002-05-02 WO disclosed