Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.36 |
| ▸ | KLK7 | P49862 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
| ▸ | PRKAR2A | P13861 | 8/20 | 0.35 |
| ▸ | PRKAR2B | P31323 | 6/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 1/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13029979 | 0.84 | TEAD4 (0.39) | TEAD4TEAD3SSTR1SSTR2SSTR4 | |
| SCHEMBL18516776 | 0.81 | F2RL1 (0.40) | TEAD4TEAD3SSTR1SSTR2SSTR4 | |
| SCHEMBL13029942 | 0.80 | TEAD4 (0.40) | TEAD4TEAD3SSTR1SSTR2SSTR4 | |
| SCHEMBL29875639 | 0.73 | KDM1A (0.43) | TEAD4TEAD3KLK7PRMT5WDR77 | |
| SCHEMBL13029983 | 0.71 | MDM2 (0.42) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL13029970 | 0.69 | MDM2 (0.41) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL13029975 | 0.67 | KCNA3 (0.44) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL18033736 | 0.64 | KCNA3 (0.44) | KLK7 | |
| SCHEMBL18516867 | 0.63 | SSTR1 (0.40) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL13030005 | 0.62 | MDM2 (0.43) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170043020-A1 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-02-16 | — | — | US | disclosed |
| US-9394371-B2 | Antibody-mediated disruption of quorum sensing in bacteria | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-07-19 | — | — | US | disclosed |
| US-9394371-B2 | Antibody-mediated disruption of quorum sensing in bacteria | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-07-19 | — | — | US | disclosed |
| US-20100291093-A1 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100291093-A1 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170043020-A1 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | CD47, TLR5, ANTXR2 | TEAD4 2895/4885TEAD3 3187/4885SSTR1 2061/4885 |
| US-20100291093-A1 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | CD47, BCR, TLR5 | TEAD4 2819/4885TEAD3 3162/4885SSTR1 1668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.