Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 6/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.34 |
| ▸ | EIF4E | P06730 | 2/20 | 0.34 |
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
| ▸ | MSTN | O14793 | 1/20 | 0.34 |
| ▸ | HRAS | P01112 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | NPR1 | P16066 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13029979 | 0.95 | TEAD4 (0.39) | F2RL1TEAD4TEAD3SLC40A1KDM1A | |
| SCHEMBL13029942 | 0.91 | TEAD4 (0.40) | F2RL1TEAD4TEAD3KDM1ARCOR1 | |
| SCHEMBL13029985 | 0.81 | TEAD4 (0.38) | TEAD4TEAD3SLC40A1KDM1ARCOR1 | |
| SCHEMBL13029975 | 0.71 | KCNA3 (0.44) | EIF4EEIF4EBP1SSTR1SSTR2SSTR4 | |
| SCHEMBL13029983 | 0.70 | MDM2 (0.42) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL21973224 | 0.69 | TEAD4 (0.44) | TEAD4TEAD3KDM1ARCOR1KEAP1 | |
| SCHEMBL16021588 | 0.69 | TEAD4 (0.44) | TEAD4TEAD3KDM1ARCOR1KEAP1 | |
| SCHEMBL29875816 | 0.69 | TEAD4 (0.44) | TEAD4TEAD3KDM1ARCOR1KEAP1 | |
| SCHEMBL13029970 | 0.68 | MDM2 (0.41) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL18033736 | 0.67 | KCNA3 (0.44) | NPR1NPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170043020-A1 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170043020-A1 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | CD47, TLR5, ANTXR2 | F2RL1 2168/4885TEAD4 2895/4885TEAD3 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.