Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131932 | 0.82 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL130161 | 0.82 | GAA (0.31) | ALDH1A1 | |
| SCHEMBL119952 | 0.80 | ALDH1A1 (0.36) | ALDH1A1NAAA | |
| SCHEMBL4839421 | 0.80 | ALDH1A1 (0.36) | ALDH1A1NAAA | |
| SCHEMBL2380925 | 0.80 | ALDH1A1 (0.39) | ALDH1A1NAAA | |
| SCHEMBL29044089 | 0.79 | ALDH1A1 (0.39) | ALDH1A1NAAA | |
| Ethane SCHEMBL28422864 | 0.78 | ALDH1A1 (0.38) | ALDH1A1NAAA | |
| SCHEMBL9635053 | 0.78 | ALDH1A1 (0.35) | ALDH1A1NAAA | |
| SCHEMBL6784510 | 0.76 | ALDH1A1 (0.39) | ALDH1A1NAAA | |
| SCHEMBL11696278 | 0.76 | KDM4E (0.33) | ALDH1A1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036453-A1 | Pyrrolopyridazinone Compound | CBR3, CBR1, CYC1 | ALDH1A1 580/4885NAAA 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.