Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.79 |
| ▸ | CDK1 | P06493 | 13/20 | 0.68 |
| ▸ | CDK5 | Q00535 | 9/20 | 0.68 |
| ▸ | CDK2 | P24941 | 7/20 | 0.68 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.68 |
| ▸ | CDK7 | P50613 | 5/20 | 0.68 |
| ▸ | CCNK | O75909 | 5/20 | 0.68 |
| ▸ | CDK12 | Q9NYV4 | 5/20 | 0.68 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.68 |
| ▸ | CDK9 | P50750 | 4/20 | 0.68 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.68 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.68 |
| ▸ | CDK4 | P11802 | 3/20 | 0.68 |
| ▸ | CCND1 | P24385 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | CCNH | P51946 | 3/20 | 0.68 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.68 |
| ▸ | CLK2 | P49760 | 2/20 | 0.68 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.68 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3508659 | 1.00 | DYRK1A (0.79) | DYRK1ACDK1CDK5CDK2CCNE1 | |
| SCHEMBL13030936 | 1.00 | DYRK1A (0.79) | DYRK1ACDK1CDK5CDK2CCNE1 | |
| SCHEMBL14964304 | 0.94 | DYRK1A (0.82) | DYRK1ACDK1CDK5CDK2CCNE1 | |
| SCHEMBL14964249 | 0.94 | DYRK1A (0.82) | DYRK1ACDK1CDK5CDK2CCNE1 | |
| SCHEMBL13030940 | 0.89 | DYRK1A (1.00) | DYRK1ACDK1CDK5CDK2CCNE1 | |
| SCHEMBL14964582 | 0.89 | DYRK1A (1.00) | DYRK1ACDK1CDK5CDK2CCNE1 | |
| SCHEMBL13030939 | 0.89 | DYRK1A (1.00) | DYRK1ACDK1CDK5CDK2CCNE1 | |
| SCHEMBL13072058 | 0.84 | KDM4E (0.60) | DYRK1ACDK1CDK5CDK2CCNE1 | |
| SCHEMBL13030951 | 0.83 | DYRK1A (0.92) | DYRK1ACDK1CDK5CDK2CCNE1 | |
| SCHEMBL18106095 | 0.82 | CDK1 (0.68) | DYRK1ACDK1CDK5CDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450342-B2 | Perharidines as CDK inhibitors | CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-05-28 | — | — | US | disclosed |
| US-8450342-B2 | Perharidines as CDK inhibitors | CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-05-28 | — | — | US | disclosed |
| US-8450342-B2 | Perharidines as CDK inhibitors | CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-05-28 | — | — | US | disclosed |
| US-20100280065-A1 | PERHARIDINES AS CDK INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-11-04 | — | — | US | disclosed |
| US-20100280065-A1 | PERHARIDINES AS CDK INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-11-04 | — | — | US | disclosed |
| WO-2009034411-A1 | PERHARIDINES AS CDK INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009034475-A2 | PERHARIDINES AS CDK INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280065-A1 | PERHARIDINES AS CDK INHIBITORS | CDK4, CDK9, CDK7 | DYRK1A 1090/4885CDK1 10/4885CDK5 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.