Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.50 |
| ▸ | DPP4 | P27487 | 3/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.50 |
| ▸ | FAP | Q12884 | 1/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.42 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.40 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824161 | 0.85 | DPP7 (0.52) | DPP7DPP4DPP8FAPDPP9 | |
| SCHEMBL30612345 | 0.85 | DPP7 (0.52) | DPP7DPP4DPP8FAPDPP9 | |
| SCHEMBL7080188 | 0.82 | CHRM1 (0.41) | DPP7DPP4DPP8FAPDPP9 | |
| SCHEMBL7080195 | 0.82 | CHRM1 (0.41) | DPP7DPP4DPP8FAPDPP9 | |
| SCHEMBL30612344 | 0.81 | L3MBTL1 (0.51) | DPP7DPP4DPP8FAPDPP9 | |
| SCHEMBL17152285 | 0.80 | DPP8 (0.53) | DPP7DPP4DPP8DPP9CYP3A4 | |
| SCHEMBL26039093 | 0.77 | DPP4 (0.51) | DPP7DPP4DPP8FAPDPP9 | |
| SCHEMBL3544639 | 0.77 | DPP8 (0.43) | DPP8DPP9MEN1KMT2A | |
| SCHEMBL3544637 | 0.77 | DPP8 (0.43) | DPP8DPP9MEN1KMT2A | |
| SCHEMBL25754647 | 0.77 | DPP8 (0.47) | DPP8CYP3A4CYP2C19CHRM1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834007-B2 | CGRP antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-11-16 | — | — | US | disclosed |
| US-20070049577-A1 | CGRP antagonists | BRISTOL-MYERS SQUIBB COMPANY | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049577-A1 | CGRP antagonists | CALCRL, CALCR, CALCA | DPP7 3449/4885DPP4 3777/4885DPP8 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.