Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1683539 | 0.98 | ALOX15 (0.40) | ALOX15TSHRALDH1A1THRBCHRM2 | |
| Iodide SCHEMBL1302592 | 0.96 | ALOX15 (0.39) | ALOX15TSHRALDH1A1THRBCHRM2 | |
| Fluoride Ion SCHEMBL1302596 | 0.96 | ALOX15 (0.39) | ALOX15TSHRALDH1A1THRBCHRM2 | |
| Hydrochloric Acid SCHEMBL980810 | 0.96 | ALOX15 (0.43) | ALOX15TSHRALDH1A1THRBCHRM2 | |
| Iodide SCHEMBL27827608 | 0.94 | ALOX15 (0.38) | ALOX15TSHRALDH1A1THRB | |
| Acrylamide SCHEMBL29204848 | 0.89 | TSHR (0.33) | ALOX15TSHRALDH1A1THRB | |
| SCHEMBL28029272 | 0.85 | ALDH1A1 (0.33) | ALOX15TSHRALDH1A1THRB | |
| Bromide SCHEMBL1303549 | 0.85 | ALDH1A1 (0.39) | ALOX15TSHRALDH1A1THRB | |
| Bromide SCHEMBL9820985 | 0.83 | TSHR (0.37) | TSHRALDH1A1THRB | |
| SCHEMBL3760083 | 0.83 | TSHR (0.37) | ALOX15TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117990906-A | Thrombin-antithrombin complex assay reagent and assay method | 普和希株式会社 | 2024-05-07 | — | — | CN | disclosed |
| CN-104375396-A | Method for preparing color carbon powder by adopting suspension polymerization method | HUBEI DINGLONG CHEMICAL CO LTD | 2015-02-25 | — | — | CN | disclosed |
| CN-102736456-B | Positive-charge color toner and preparation method thereof | HUBEI DINGLONG CHEMICAL CO LTD | 2014-03-19 | — | — | CN | disclosed |
| CN-102066486-B | Gel composition, method for preparing the same, and impact-resistant absorbing material using the same | 3M INNOVATIVE PROPERTIES CO | 2013-08-14 | — | — | CN | disclosed |
| CN-102736456-A | Positive-charge color toner and preparation method thereof | HUBEI DINGLONG CHEMICAL CO LTD | 2012-10-17 | — | — | CN | disclosed |
| CN-102349364-A | Electromagnetic wave shielding gel-like composition | 3M INNOVATIVE PROPERTIES CO | 2012-02-08 | — | — | CN | disclosed |
| EP-2387866-A1 | ELECTROMAGNETIC WAVE SHIELDING GEL-LIKE COMPOSITION | 3M Innovative Properties Company (US) | 2011-11-23 | — | — | EP | disclosed |
| US-20110268950-A1 | Electromagnetic Wave Shielding Gel-Like Composition | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-11-03 | — | — | US | disclosed |
| US-8038066-B2 | Laser scanner with deformable lens | HAND HELD PRODUCTS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| CN-102066486-A | Gel composition, method for preparing the same, and impact-resistant absorbing material using the same | 3M INNOVATIVE PROPERTIES CO | 2011-05-18 | — | — | CN | disclosed |
| WO-2010083075-A1 | ELECTROMAGNETIC WAVE SHIELDING GEL-LIKE COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-07-22 | — | — | WO | disclosed |