Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.52 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.52 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.52 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.52 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.52 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.52 |
| ▸ | REN | P00797 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | NPY4R | P50391 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12294941 | 0.79 | REN (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12294934 | 0.78 | PSEN1 (0.51) | CAPN1CAPN2PSEN1PSEN2APH1B | |
| SCHEMBL10825170 | 0.78 | MEN1 (0.68) | CAPN1CAPN2MEN1ALDH1A1HPGD | |
| SCHEMBL12294937 | 0.78 | PSEN1 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10825385 | 0.76 | HPGD (0.66) | CAPN1CAPN2MEN1ALDH1A1HPGD | |
| SCHEMBL10825380 | 0.76 | HPGD (0.66) | CAPN1CAPN2MEN1ALDH1A1HPGD | |
| SCHEMBL13033370 | 0.75 | CAPN1 (0.46) | CAPN1CAPN2RENMEN1ALDH1A1 | |
| SCHEMBL7309615 | 0.74 | MAPT (0.56) | MEN1KMT2APSMB5 | |
| SCHEMBL23447225 | 0.74 | PTPN1 (0.56) | CAPN1RENOPRM1OPRD1CTSK | |
| SCHEMBL25379202 | 0.74 | PTGER4 (0.54) | CAPN1CAPN2CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100278927-A1 | POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278927-A1 | POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION | NCL, POLN, CHMP4B | CAPN1 1356/4885CAPN2 1249/4885PSEN1 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.