Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 6/20 | 0.51 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.51 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.51 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.51 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.51 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12294937 | 0.89 | PSEN1 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12294941 | 0.86 | REN (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12294935 | 0.80 | FAAH (0.50) | — | |
| SCHEMBL29389760 | 0.79 | OPRK1 (0.57) | OPRM1OPRD1OPRK1CTSB | |
| SCHEMBL30434531 | 0.79 | OPRK1 (0.56) | OPRM1OPRD1OPRK1CTSB | |
| SCHEMBL29569557 | 0.79 | OPRK1 (0.56) | OPRM1OPRD1OPRK1CTSB | |
| SCHEMBL15004075 | 0.78 | KISS1R (0.47) | OPRM1OPRD1OPRK1CTSBKISS1R | |
| SCHEMBL29568812 | 0.78 | OPRK1 (0.55) | OPRM1OPRD1OPRK1CTSB | |
| SCHEMBL13033364 | 0.78 | CAPN1 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31236826 | 0.78 | OPRK1 (0.62) | OPRM1OPRD1OPRK1CTSBNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2544701-B1 | POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF | UNIV UTAH RES FOUND (US) | 2019-08-14 | — | — | EP | disclosed |
| US-9289510-B2 | Polymeric drug delivery conjugates and methods of making and using thereof | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20130156722-A1 | POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2011112482-A2 | POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2011-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156722-A1 | POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF | CD44, MMP7, MMP26 | PSEN1 3954/4885PSEN2 4131/4885APH1B 2903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.