Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 17/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 17/20 | 1.00 |
| ▸ | GAA | P10253 | 9/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.78 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.64 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.64 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14709352 | 0.88 | MEN1 (1.00) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL24743578 | 0.78 | PBRM1 (1.00) | MEN1KMT2AGAAL3MBTL1PBRM1 | |
| SCHEMBL24743579 | 0.78 | PBRM1 (0.69) | MEN1KMT2AGAAL3MBTL1PBRM1 | |
| SCHEMBL24743573 | 0.77 | PBRM1 (1.00) | MEN1KMT2AGAAPBRM1SMARCA2 | |
| SCHEMBL24743574 | 0.77 | PBRM1 (0.70) | MEN1KMT2AGAAL3MBTL1PBRM1 | |
| SCHEMBL14709218 | 0.75 | MEN1 (0.65) | MEN1KMT2AGAAL3MBTL1PBRM1 | |
| SCHEMBL12783883 | 0.75 | MEN1 (1.00) | MEN1KMT2AGAAL3MBTL1PBRM1 | |
| SCHEMBL14709216 | 0.73 | MEN1 (1.00) | MEN1KMT2AGAAL3MBTL1PBRM1 | |
| SCHEMBL13035695 | 0.69 | MEN1 (1.00) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL11568615 | 0.69 | MEN1 (1.00) | MEN1KMT2AGAAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297046-A1 | Compositions and Methods Related to Fructosamine-3-Kinase Inhibitors | DYNAMIS THERAPEUTICS, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100297046-A1 | Compositions and Methods Related to Fructosamine-3-Kinase Inhibitors | DYNAMIS THERAPEUTICS, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| WO-2007117394-A2 | COMPOSITIONS AND METHODS RELATED TO FRUCTOSAMINE-3-KINASE INHIBITORS | DYNAMIS THERAPEUTICS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297046-A1 | Compositions and Methods Related to Fructosamine-3-Kinase Inhibitors | FN3K, ROS1, FN3KRP | MEN1 4765/4885KMT2A 2677/4885GAA 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.