Sugi Predict

Sugi Predict / Targets / FN3K

FN3K

Fructosamine-3-kinase · Q9H479 · FN3K on Sugi Atlas →

0 patent compounds predicted against FN3K, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to FN3K by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of a Basal/Pre-Meal Insulin Strategy (Detemir/Aspart) on Insulin Secretion and Action in Type 2 Diabetes PHASE4COMPLETED
The Effect of the Preoperative Oral Carbohydrate Attenuating Immediate Postoperative Insulin Resistance on PI3K Dependent Signaling Pathway PHASE4COMPLETED
Short-Term Metformin Use in Young, Healthy Adults: Impacts on Exercise Capacity PHASE4COMPLETED
Compare the Impact of Xuezhikang and Atorvastatin on Glucose Metabolism in Dyslipidemia Patients With Prediabetes PHASE4COMPLETED
Molecular Mechanisms of Type 2 Diabetes Mellitus PHASE4COMPLETED
Mitochondrial Oxidation and Insulin Resistance in Burn Patients Treated With Fenofibrate PHASE2/PHASE3WITHDRAWN
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus PHASE3UNKNOWN
Ketohexokinase Inhibition in NAFLD PHASE2COMPLETED
STAR Cape+BKM120 MBC With Brain Met PHASE2COMPLETED
HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes PHASE2RECRUITING
Acute Effect of HP-211 (Axulin) on Blood Glucose and Serum Insulin Responses in Healthy Lean and Overweight Humans PHASE1COMPLETED
3'-Deoxy-3'-[18F] Fluorothymidine and Fludeoxyglucose F 18 PET Scans in Evaluating Response to Cetuximab, Cisplatin, and Radiation Therapy in Patients With Advanced Cancer of the Oropharynx, Larynx, or Hypopharynx EARLY_PHASE1COMPLETED
Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer EARLY_PHASE1COMPLETED
The Role of Sugars in Fat Accumulation in the Liver nanRECRUITING
Accuracy of Hemoglobin A1C to Predict Glycemia in HIV nanCOMPLETED
Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome nanCOMPLETED
Dried Fruit and Postprandial Glycemia Trial nanUNKNOWN
Patient With Any Pathology (According to the Appreciation of the Investigator) Which Could Disturb the Participation in the Study nanUNKNOWN
Metabolic Signalling in Muscle- and Adipose-tissue Following Insulin Withdrawal and Growth Hormone Injection. nanCOMPLETED
Effect of Acute Fructose Load in Human nanCOMPLETED
Influence of DPP-4 on Inflammatory Parameters in Diabetics: Gender Aspects nanUNKNOWN
Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation nanCOMPLETED
Protein Intake and Step Reduction in Older Adults nanCOMPLETED
The Effect of Blueberries on Enhancing Insulin Sensitivity in Humans: A Pilot Study nanWITHDRAWN
Omega-3 Fatty Acids Supplementation and Atherothrombotic Biomarkers in Type 2 Diabetes and Cardiovascular Disease. nanCOMPLETED
Fluorodeoxyglucose Positron Emission Tomography (FDG PET) Findings in Patients With Phenylketonuria Before and After KUVAN Therapy nanCOMPLETED
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED
Influence of Intermittent Hypoxia on Glycemic Control nanCOMPLETED
Microvascular Dysfunction and the Development of Whole-body Insulin Resistance nanCOMPLETED
Insulin Sensitivity and Testosterone Response to Aerobic Exercise Versus Added Sugar Elimination in Polycystic Ovary Syndrome Women nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a FN3K binder may also engage these)

ProteinNameSimilarity
Q9ER35 — 1.000 Q9ER35 →
FN3KRP Ketosamine-3-kinase 0.992 landscape →
Q8K274 — 0.985 Q8K274 →
O54783 — 0.954 O54783 →
Q2R483 — 0.950 Q2R483 →
Q9D4V0 — 0.949 Q9D4V0 →
Q8CG45 — 0.947 Q8CG45 →
Q5RFI8 — 0.944 Q5RFI8 →
P08836 — 0.944 P08836 →
Q9D0L4 — 0.944 Q9D0L4 →
Q9FN41 — 0.943 Q9FN41 →
A2RU49 — 0.943 A2RU49 →
Q640V9 — 0.943 Q640V9 →
O35621 — 0.942 O35621 →
Q8JGT5 — 0.942 Q8JGT5 →
ADCK1 AarF domain-containing protein kinase 1 0.942 landscape →
O55229 — 0.942 O55229 →
B8BKI7 — 0.942 B8BKI7 →
Q5R514 — 0.941 Q5R514 →
Q9DBC0 — 0.941 Q9DBC0 →
B4G0F3 — 0.941 B4G0F3 →
O35331 — 0.940 O35331 →
P13439 — 0.940 P13439 →
B9SQI7 — 0.940 B9SQI7 →
Q8NHP1 — 0.940 Q8NHP1 →
B9N1F9 — 0.940 B9N1F9 →
Q8CG76 — 0.940 Q8CG76 →
Q5I0K3 — 0.940 Q5I0K3 →
E0CSI1 — 0.940 E0CSI1 →
GLS2 Glutaminase liver isoform, mitochondrial 0.939 landscape →