Sugi Predict
/ Targets
/ FN3KRP
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
Clinical trials — most relevant to FN3KRP by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
| Mitochondrial Oxidation and Insulin Resistance in Burn Patients Treated With Fenofibrate |
PHASE2/PHASE3 | WITHDRAWN |
| The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus |
PHASE3 | UNKNOWN |
| Carboplatin Taxol Avastin in Ovarian Cancer (OVCA) |
PHASE2 | COMPLETED |
| I/II Phase Study Evaluating M1774 in Combination With Fulvestrant in HR+ and HER2- Advanced Breast Cancers |
PHASE1/PHASE2 | NOT_YET_RECRUITING |
| A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H... |
PHASE2 | COMPLETED |
| Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors |
PHASE2 | RECRUITING |
| Biological Effects of Quercetin in COPD Phase II |
PHASE2 | UNKNOWN |
| STAR Cape+BKM120 MBC With Brain Met |
PHASE2 | COMPLETED |
| Autologous Cytokine Induced Killer Cells (CIK) for Chronic Myeloid Leukemia (CML) Patients on Standard Drug Therapy |
PHASE2 | COMPLETED |
| Phase II Study of Vandetanib in Individuals With Kidney Cancer |
PHASE2 | COMPLETED |
| Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma |
PHASE1 | COMPLETED |
| Safety and Tolerability Study of TAK-165 in Subjects With Tumors Expressing HER2 |
PHASE1 | COMPLETED |
| Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors |
PHASE1 | COMPLETED |
| FAK Inhibitor in Patients With Advanced Solid Tumors |
PHASE1 | NOT_YET_RECRUITING |
| Defining the Triple Negative Breast Cancer Kinome Response to GSK1120212 |
EARLY_PHASE1 | COMPLETED |
| Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer |
EARLY_PHASE1 | COMPLETED |
| A Retro-/Prospective, Non-interventional, Cohort Study in Adult Patients With Locally Advanced or Metastatic Tumors With a Neurotrophic Tyrosine Receptor Kinase (NTRK) Gene Fusion, Treated With Larotrectinib |
nan | COMPLETED |
| p-AKT Expression on Clinical Outcomes in Malignant Lymphoma |
nan | COMPLETED |
| PCM1-JAK2 in Therapy Related Neoplasms |
nan | UNKNOWN |
| Fluorodeoxyglucose Positron Emission Tomography (FDG PET) Findings in Patients With Phenylketonuria Before and After KUVAN Therapy |
nan | COMPLETED |
| Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome |
nan | COMPLETED |
| NTRK 1,2,3 Rearrangements in Patients With Solid Tumors |
nan | ACTIVE_NOT_RECRUITING |
| Metabolic Signalling in Muscle- and Adipose-tissue Following Insulin Withdrawal and Growth Hormone Injection. |
nan | COMPLETED |
| Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA |
nan | RECRUITING |
| Tumor Kinase Inhibitor Concentrations Measured by PET |
nan | COMPLETED |
| Association Between Intakes of Protein, Calcium and Milk With Gene Expression and Linear Growth of School Aged Children |
nan | COMPLETED |
| Role of Nitric Oxide in Diabetic Patients With Erectile Dysfunction |
nan | COMPLETED |
| The Role of Sugars in Fat Accumulation in the Liver |
nan | RECRUITING |
| Dried Fruit and Postprandial Glycemia Trial |
nan | UNKNOWN |
| Evaluation of Human Melanocytes After the Use of PRP Versus Fractional CO2 Laser in Vitiligo |
nan | UNKNOWN |
Related proteins — ESM-2 sequence neighbours (a FN3KRP binder may also engage these)