Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | POLG | P54098 | 1/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13036650 | 0.92 | TYMP (0.41) | TYMPPOLBLMNAPDE3ACACNA1F | |
| SCHEMBL6885494 | 0.88 | POLB (0.53) | TYMPPOLBLMNAPDE3ACACNA1F | |
| SCHEMBL6885492 | 0.88 | POLB (0.53) | TYMPPOLBLMNAPDE3ACACNA1F | |
| SCHEMBL12885730 | 0.87 | TYMP (0.38) | TYMPPOLBLMNAPDE3ACACNA1F | |
| SCHEMBL13036642 | 0.87 | TYMP (0.38) | TYMPPOLBLMNAPDE3ACACNA1F | |
| SCHEMBL13036664 | 0.86 | TYMP (0.38) | TYMPPOLBLMNAPDE3ACACNA1F | |
| SCHEMBL14066269 | 0.85 | POLB (0.50) | TYMPPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL837249 | 0.84 | TYMP (0.37) | TYMPPOLBLMNAPDE3ACACNA1F | |
| SCHEMBL874315 | 0.84 | POLB (0.49) | TYMPPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL20527120 | 0.83 | TYMP (0.41) | TYMPPOLBLMNAPDE3ACACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829548-B2 | Compounds useful in the treatment of HIV | MEDIVIR AB (SE) | 2010-11-09 | — | — | US | disclosed |
| US-7829548-B2 | Compounds useful in the treatment of HIV | MEDIVIR AB (SE) | 2010-11-09 | — | — | US | disclosed |
| EP-1835916-B1 | COMPOUNDS USEFUL IN THE TREATMENT OF HIV | MEDIVIR AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| US-20080176817-A1 | Compounds Useful in the Treatment of Hiv | MEDIVIR AB (SE) | 2008-07-24 | — | — | US | disclosed |
| US-20080176817-A1 | Compounds Useful in the Treatment of Hiv | MEDIVIR AB (SE) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176817-A1 | Compounds Useful in the Treatment of Hiv | MTAP, NUDT1, TYMP | TYMP 3/4885POLB 41/4885LMNA 2482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.