Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TYMP | P19971 | 3/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | DUT | P33316 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885492 | 1.00 | POLB (0.53) | POLBTYMPP2RY2P2RY4P2RY6 | |
| SCHEMBL18817978 | 0.94 | POLB (0.49) | POLBTYMPP2RY2P2RY4P2RY6 | |
| SCHEMBL8491776 | 0.93 | POLB (0.59) | POLBTYMPP2RY2P2RY4P2RY6 | |
| SCHEMBL13036643 | 0.88 | TYMP (0.42) | POLBTYMPP2RY2P2RY4P2RY6 | |
| SCHEMBL13036650 | 0.87 | TYMP (0.41) | POLBTYMPP2RY2P2RY4P2RY6 | |
| SCHEMBL26647528 | 0.87 | TYMP (0.58) | POLBTYMPTYMSADRB1DNMT1 | |
| SCHEMBL30274788 | 0.87 | TYMP (0.58) | POLBTYMPTYMSADRB1DNMT1 | |
| SCHEMBL24115327 | 0.87 | TYMP (0.48) | POLBTYMPP2RY6NT5ETYMS | |
| SCHEMBL31556049 | 0.87 | TYMP (0.48) | POLBTYMPP2RY6NT5ETYMS | |
| SCHEMBL20596260 | 0.87 | TYMP (0.48) | POLBTYMPP2RY6NT5ETYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825331-B2 | DIAGNOSTIC HYBRIDIZATION PROBES; BIOCHEMICAL CONJUGATION | ISIS PHARMACEUTICALS, INC. | 2004-11-30 | — | — | US | disclosed |
| US-20030113769-A1 | Aminooxy functionalized oligomers, oligomer arrays and methods of using them | IONIS PHARMACEUTICALS, INC. | 2003-06-19 | — | — | US | disclosed |
| US-6576752-B1 | Oligonucleotide comprising a plurality of nucleotide units of given structure; useful for diagnostic, therapeutic and investigative purposes | ISIS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030113769-A1 | Aminooxy functionalized oligomers, oligomer arrays and methods of using them | RNGTT, RNMT, DCLRE1B | POLB 32/4885TYMP 627/4885P2RY2 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.