Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818354 | 0.84 | — | — | |
| SCHEMBL8048476 | 0.83 | AR (0.31) | — | |
| SCHEMBL1469728 | 0.82 | ACACB (0.38) | ACACBLPAR6LPAR1LPAR4LPAR5 | |
| SCHEMBL5484842 | 0.80 | MEN1 (0.35) | ACACBLPAR6LPAR1LPAR4LPAR5 | |
| SCHEMBL1469110 | 0.80 | ACACB (0.40) | ACACBLPAR6LPAR1LPAR4LPAR5 | |
| SCHEMBL4567273 | 0.80 | PRKCA (0.42) | ACACBMEN1KMT2APRKCA | |
| SCHEMBL13017848 | 0.78 | MEN1 (0.42) | ACACBLPAR6LPAR1LPAR4LPAR5 | |
| SCHEMBL26399931 | 0.77 | — | — | |
| SCHEMBL5017987 | 0.76 | PRKCA (0.46) | CTSKPRKCAPRKCD | |
| SCHEMBL15503246 | 0.75 | PRKCA (0.56) | ACACBLPAR6LPAR1LPAR4LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825238-B2 | Antiviral methods employing double esters of 2′, 3′-dideoxy-3′-fluoroguanosine | MEDIVIR AB (SE) | 2010-11-02 | — | — | US | disclosed |