Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11172217 | 0.88 | TSHR (0.43) | PRKCATSHRLMNAMEN1CYP1A2 | |
| SCHEMBL12323575 | 0.84 | PRKCA (0.51) | PRKCATSHRLMNAMEN1CYP1A2 | |
| SCHEMBL1469728 | 0.84 | ACACB (0.38) | PRKCAMEN1KMT2AACACBALDH1A1 | |
| SCHEMBL2957512 | 0.84 | PRKCA (0.51) | PRKCATSHRLMNAMEN1CYP1A2 | |
| SCHEMBL1584634 | 0.83 | — | — | |
| SCHEMBL3801260 | 0.83 | PRKCA (0.44) | PRKCATSHRLMNAMEN1CYP1A2 | |
| SCHEMBL425452 | 0.82 | TDP1 (0.50) | PRKCATSHRLMNAMEN1CYP1A2 | |
| SCHEMBL1469110 | 0.82 | ACACB (0.40) | PRKCAMEN1KMT2AACACB | |
| SCHEMBL5484842 | 0.82 | MEN1 (0.35) | PRKCAMEN1KMT2AACACBALDH1A1 | |
| SCHEMBL5192564 | 0.82 | TDP1 (0.50) | PRKCATSHRLMNAMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9849129-B2 | Sodium channel blockers for skin disorders | PARION SCIENCES, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20170020870-A1 | SODIUM CHANNEL BLOCKERS FOR SKIN DISORDERS | PARION SCIENCES, INC. | 2017-01-26 | — | — | US | disclosed |
| US-8778864-B2 | Polyglyceryl compounds and compositions | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8455418-B2 | Polyglyceryl compounds comprising a methyl glucoside or sorbitan remnant and compositions containing same | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-8394755-B2 | Polyglyceryl compounds and compositions | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2013-03-12 | — | — | US | disclosed |
| US-8211850-B2 | Polyglyceryl compounds and compositions | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2012-07-03 | — | — | US | disclosed |
| US-20120122755-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | JOHNSON & JOHNSON CONSUMER INC. | 2012-05-17 | — | — | US | disclosed |
| US-20120123103-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | KENVUE BRANDS LLC | 2012-05-17 | — | — | US | disclosed |
| US-20120122758-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | KENVUE BRANDS LLC | 2012-05-17 | — | — | US | disclosed |
| US-20120123104-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | KENVUE BRANDS LLC | 2012-05-17 | — | — | US | disclosed |
| US-7858159-B2 | Photocurable composition for sealant, liquid crystal sealant, and liquid crystal panel | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2010-12-28 | — | — | US | disclosed |
| US-20090131550-A1 | PHOTOCURABLE COMPOSITION FOR SEALANT, LIQUID CRYSTAL SEALANT, AND LIQUID CRYSTAL PANEL | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2009-05-21 | — | — | US | disclosed |
| US-5128234-A | PRODUCTION OF PHOTOPOLYMERIC FLEXOGRAPHIC RELIEF PRINTING PLATES | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123104-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | PHOSPHO1, SGMS1, SGMS2 | PRKCA 2464/4885TSHR 4727/4885LMNA 705/4885 |
| US-20120122755-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | PHOSPHO1, SGMS1, SGMS2 | PRKCA 2464/4885TSHR 4727/4885LMNA 705/4885 |
| US-20090131550-A1 | PHOTOCURABLE COMPOSITION FOR SEALANT, LIQUID CRYSTAL SEALANT, AND LIQUID CRYSTAL PANEL | TRPA1, ANXA1, ANXA11 | PRKCA 4789/4885TSHR 4590/4885LMNA 1845/4885 |
| US-20120122758-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | PHOSPHO1, SGMS1, SGMS2 | PRKCA 2464/4885TSHR 4727/4885LMNA 705/4885 |
| US-20120123103-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | PHOSPHO1, SGMS1, SGMS2 | PRKCA 2464/4885TSHR 4727/4885LMNA 705/4885 |
| US-20170020870-A1 | SODIUM CHANNEL BLOCKERS FOR SKIN DISORDERS | SCNN1B, SCNN1A, SCNN1G | PRKCA 1361/4885TSHR 2482/4885LMNA 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.