Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 8/20 | 0.53 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.52 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9441690 | 1.00 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL14306379 | 1.00 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL12562198 | 0.87 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL14828718 | 0.87 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL9462009 | 0.87 | SLC1A2 (0.66) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL1168551 | 0.87 | SLC1A2 (0.66) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL1168553 | 0.87 | SLC1A2 (0.66) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL19939555 | 0.84 | HPGDS (0.61) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL15833197 | 0.84 | HPGDS (0.61) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL14318468 | 0.84 | HPGDS (0.61) | ALDH1A1KMT2AMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825238-B2 | Antiviral methods employing double esters of 2′, 3′-dideoxy-3′-fluoroguanosine | MEDIVIR AB (SE) | 2010-11-02 | — | — | US | disclosed |