Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13039984 | 0.86 | ADORA3 (0.45) | TSHRTP53CA1CA2GAA | |
| SCHEMBL14080715 | 0.83 | ADORA3 (0.43) | CA1CA2MEN1KMT2AADORA3 | |
| SCHEMBL10870487 | 0.81 | CYP3A4 (0.50) | TSHRTP53CA1CA2MEN1 | |
| SCHEMBL13039991 | 0.80 | CA1 (0.36) | TSHRTP53CA1CA2GAA | |
| SCHEMBL14357615 | 0.76 | ESR1 (0.49) | TP53GAAMEN1KMT2ACYP3A4 | |
| SCHEMBL1598844 | 0.76 | LMNA (0.48) | TSHRTP53CA1CA2GAA | |
| SCHEMBL19482467 | 0.76 | ELANE (0.54) | TSHRCA2L3MBTL1MEN1KMT2A | |
| SCHEMBL6152948 | 0.76 | CYP3A4 (0.46) | TSHRCA1CA2GAAMMP2 | |
| SCHEMBL13039980 | 0.75 | CA1 (0.36) | TSHRTP53CA1CA2GAA | |
| SCHEMBL15887464 | 0.75 | MAPT (0.50) | TP53L3MBTL1MEN1KMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829252-B2 | Imaging member | XEROX CORPORATION (US) | 2010-11-09 | — | — | US | disclosed |