Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KLK7 | P49862 | 6/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.34 |
| ▸ | YAP1 | P46937 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13040204 | 1.00 | L3MBTL1 (0.39) | L3MBTL1KLK7ITGB3ITGA2BGPR119 | |
| SCHEMBL30855078 | 0.89 | KLK7 (0.36) | L3MBTL1KLK7YAP1PPARAKLK5 | |
| SCHEMBL3411574 | 0.89 | ITGB3 (0.35) | L3MBTL1ITGB3ITGA2B | |
| SCHEMBL3407057 | 0.89 | ITGB3 (0.35) | L3MBTL1ITGB3ITGA2B | |
| SCHEMBL31043213 | 0.78 | USP30 (0.35) | KLK7GPR119KLK5PRSS1PRSS2 | |
| SCHEMBL21911497 | 0.78 | USP30 (0.35) | KLK7GPR119KLK5PRSS1PRSS2 | |
| SCHEMBL13040212 | 0.77 | L3MBTL1 (0.38) | L3MBTL1KLK7ITGB3ITGA2BGPR119 | |
| SCHEMBL13040206 | 0.77 | L3MBTL1 (0.38) | L3MBTL1KLK7ITGB3ITGA2BGPR119 | |
| SCHEMBL3410203 | 0.76 | L3MBTL1 (0.44) | L3MBTL1KLK7PPARAKLK5PRSS1 | |
| SCHEMBL13040201 | 0.76 | L3MBTL1 (0.44) | L3MBTL1KLK7PPARAKLK5PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280243-A1 | PROCESS FOR PRODUCTION OF 4- (SUBSTITUTED PHENYL) HEXAHYDROPYRIDO [2,1-C] [1,4] OXAZIN-6-ONE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280243-A1 | PROCESS FOR PRODUCTION OF 4- (SUBSTITUTED PHENYL) HEXAHYDROPYRIDO [2,1-C] [1,4] OXAZIN-6-ONE | PSEN1, APP, BACE1 | L3MBTL1 4836/4885KLK7 2555/4885ITGB3 4793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.