Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409147 | 0.86 | CYP1A2 (0.50) | SMN1; SMN2HTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27253773 | 0.80 | CYP1A2 (0.43) | SMN1; SMN2HTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL21032722 | 0.78 | CRBN (0.39) | SMN1; SMN2HTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3648566 | 0.77 | CYP3A4 (0.44) | SMN1; SMN2HTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13656082 | 0.77 | CRBN (0.36) | HTTEPHX1CA2KDM4EPTGS1 | |
| SCHEMBL11270016 | 0.77 | LMNA (0.36) | SMN1; SMN2HTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14274520 | 0.75 | HTT (0.40) | SMN1; SMN2HTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1515251 | 0.75 | — | — | |
| SCHEMBL14571085 | 0.74 | CRBN (0.47) | KMT2ALMNAEPHX1CA2KDM4E | |
| Methylamine SCHEMBL8907491 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846903-B2 | Acyl-urea derivatives and uses thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2014-09-30 | — | — | US | disclosed |
| US-20100280124-A1 | ACYL-UREA DERIVATIVES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280124-A1 | ACYL-UREA DERIVATIVES AND USES THEREOF | ABAT, HDAC6, ACAT1 | SMN1; SMN2 1359/4885HTT 531/4885CYP1A2 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.