Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13040597 | 0.84 | PARP1 (0.30) | PARP1 | |
| SCHEMBL13040595 | 0.75 | PARP1 (0.38) | PARP1 | |
| SCHEMBL14869156 | 0.71 | CCR1 (0.36) | CCR1CCR5CCR8PARP1KDM4E | |
| SCHEMBL633373 | 0.69 | HSD17B10 (0.32) | KDM4E | |
| SCHEMBL14869197 | 0.68 | CCR1 (0.33) | CCR1CCR5CCR8PARP1KDM4E | |
| SCHEMBL13077461 | 0.68 | POLB (0.31) | CCR1CCR5CCR8PARP1 | |
| SCHEMBL377288 | 0.65 | CCR1 (0.38) | CCR1CCR5CCR8PARP1KDM4E | |
| SCHEMBL13040588 | 0.64 | CCR1 (0.56) | CCR1CCR5CCR8PARP1KDM4E | |
| SCHEMBL13077888 | 0.64 | MEN1 (0.32) | — | |
| SCHEMBL23905544 | 0.64 | HCAR2 (0.37) | CCR1CCR5CCR8PARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280068-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280068-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A1, CYP3A7, CYP1A2 | CCR1 2987/4885CCR5 3893/4885CCR8 4261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.