Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12181891 | 0.90 | HPGDS (0.35) | POLB | |
| SCHEMBL1927591 | 0.89 | POLB (0.31) | POLB | |
| SCHEMBL13077888 | 0.89 | MEN1 (0.32) | — | |
| SCHEMBL13077466 | 0.88 | POLB (0.30) | POLB | |
| SCHEMBL12181876 | 0.88 | ALDH1A1 (0.32) | POLB | |
| SCHEMBL13077460 | 0.87 | SCN9A (0.31) | — | |
| SCHEMBL14859875 | 0.87 | PARP1 (0.34) | PARP1 | |
| SCHEMBL633818 | 0.86 | PARP1 (0.33) | POLBPARP1 | |
| SCHEMBL3727982 | 0.86 | — | — | |
| SCHEMBL3732835 | 0.86 | PARP1 (0.36) | POLBPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130096156-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-18 | — | — | US | disclosed |
| US-20130096156-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-18 | — | — | US | disclosed |
| US-20130096156-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-18 | — | — | US | disclosed |
| EP-2397467-A1 | Quinoline derivatives as fungicides | Syngenta Participations AG (CH) | 2011-12-21 | — | — | EP | disclosed |
| EP-2397467-A1 | Quinoline derivatives as fungicides | Syngenta Participations AG (CH) | 2011-12-21 | — | — | EP | disclosed |
| WO-2011154240-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-15 | — | — | WO | disclosed |
| US-20100280068-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096156-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP4X1, CYP3A7 | POLB 4679/4885PARP1 4322/4885CCR1 2008/4885 |
| US-20100280068-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A1, CYP3A7, CYP1A2 | POLB 4575/4885PARP1 4148/4885CCR1 2987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.