Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 14/20 | 0.38 |
| ▸ | KDR | P35968 | 9/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.38 |
| ▸ | FLT1 | P17948 | 8/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13042323 | 0.81 | FGFR1 (0.46) | FGFR1KDRPDGFRBFLT1CHEK1 | |
| SCHEMBL13042357 | 0.81 | FGFR1 (0.46) | FGFR1KDRPDGFRBFLT1CHEK1 | |
| SCHEMBL13042348 | 0.81 | PDGFRB (0.40) | FGFR1KDRPDGFRBFLT1CHEK1 | |
| SCHEMBL3728541 | 0.81 | NPC1 (0.56) | FGFR1KDRPDGFRBFLT1CHEK1 | |
| SCHEMBL13042373 | 0.80 | KMT2A (0.48) | FGFR1KDRPDGFRBFLT1CHEK1 | |
| SCHEMBL13042356 | 0.80 | RAB9A (0.47) | FGFR1KDRPDGFRBFLT1CHEK1 | |
| SCHEMBL13042548 | 0.79 | FGFR1 (0.38) | FGFR1KDRPDGFRBFLT1CHEK1 | |
| SCHEMBL13042352 | 0.79 | NPBWR1 (0.48) | FGFR1KDRPDGFRBFLT1CHEK1 | |
| SCHEMBL13076647 | 0.79 | MAPK10 (0.46) | FGFR1KDRPDGFRBFLT1CHEK1 | |
| SCHEMBL13042544 | 0.78 | ESR1 (0.49) | FGFR1KDRPDGFRBFLT1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492374-B2 | Azaazulene compounds | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-07-23 | — | — | US | disclosed |
| US-20100280012-A1 | AZAAZULENE COMPOUNDS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280012-A1 | AZAAZULENE COMPOUNDS | AZI2, CYP51A1, CYP3A5 | FGFR1 1577/4885KDR 3950/4885PDGFRB 2688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.