⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348934 | 0.70 | — | — | |
| SCHEMBL2814353 | 0.69 | HSP90AA1 (0.52) | — | |
| SCHEMBL30595872 | 0.69 | HSP90AA1 (0.52) | — | |
| Pyrimidine SCHEMBL27362946 | 0.69 | CYP2A6 (0.42) | — | |
| SCHEMBL23302383 | 0.69 | — | — | |
| SCHEMBL3090384 | 0.67 | — | — | |
| SCHEMBL26376426 | 0.67 | — | — | |
| SCHEMBL13910999 | 0.67 | HSP90AA1 (0.50) | — | |
| SCHEMBL8483679 | 0.66 | CYP2D6 (0.51) | — | |
| SCHEMBL17641612 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4025570-A1 | HYDANTOIN DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2022-07-13 | — | — | EP | claimed |
| WO-2021043245-A1 | HYDANTOIN DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-03-11 | — | — | WO | claimed |
| US-20190016745-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2019-01-17 | — | — | US | claimed |
| EP-3400231-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | Technion Research & Development Foundation Limited (IL) | 2018-11-14 | — | — | EP | claimed |
| EP-3344641-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | Eloxx Pharmaceuticals Ltd. (IL) | 2018-07-11 | — | — | EP | claimed |
| CN-107056714-A | Replace the preparation method of cyano-benzene oxygen pyrimidine radicals phenyl acrylate derivative | 安道麦马克西姆有限公司 | 2017-08-18 | — | — | CN | claimed |
| WO-2017118967-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2017-07-13 | — | — | WO | claimed |
| CN-105189502-B | N (4 (base of azaindazole 6) phenyl) sulfonamide and its purposes as medicine | 赛诺菲 | 2017-05-31 | — | — | CN | claimed |
| WO-2017037719-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | ELOXX PHARMACEUTICALS LTD. (IL) | 2017-03-09 | — | — | WO | claimed |
| US-8344142-B2 | perylenetetracarboxylic diimide core having side chains (groups or mesogens) attached to the core; to provide charge-transport materials having various volatilities, solubilities, crystallinity, and charge transport ability; organic light emitting diode; photovoltaic cells, light-emitting diodes | GEORGIA TECH RESEARCH CORPORATION (US) | 2013-01-01 | — | — | US | claimed |
| WO-2005124453-A2 | PERYLENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF | GEORGIA TECH RESEARCH CORPORATION (US) | 2005-12-29 | — | — | WO | claimed |
| US-20050080073-A1 | Sulfonylaminocarboxiylic acid N-arylamides as guanylate cyclase activators | AVENTIS PHARMA DEUTSCHLAND GMBH | 2005-04-14 | — | — | US | claimed |
| US-20030171352-A1 | Sulfonylaminocarboxylic acid N-arylamides as guanylate cyclase activators | AVENTIS PHARMA DEUTSCHLAND GMBH | 2003-09-11 | — | — | US | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | claimed |
| WO-2002094793-A1 | ACYLATED 4-AMINOPYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-28 | — | — | WO | claimed |
| EP-1095015-A2 | SULFONYLAMINO CARBOXYLIC ACID N-ARYLAMIDES AS GUANYLATE CYCLASE ACTIVATORS | Aventis Pharma Deutschland GmbH (DE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000002850-A2 | SULFONYLAMINO CARBOXYLIC ACID N-ARYLAMIDES AS GUANYLATE CYCLASE ACTIVATORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-01-20 | — | — | WO | claimed |
| US-5290668-A | Photographic films with waterproof layers on supports for color photography | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-01 | — | — | US | claimed |
| US-5212055-A | Pyrazoloazole coupler, bisphenol, spirobiindane | FUJI PHOTO FILM CO., LTD. (JP) | 1993-05-18 | — | — | US | claimed |