Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.40 |
| ▸ | LATS1 | O95835 | 1/20 | 0.40 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2814353 | 1.00 | HSP90AA1 (0.52) | HSP90AA1CYP2D6GRM5MAPK9MAPK14 | |
| SCHEMBL10402322 | 0.94 | HSP90AA1 (0.48) | HSP90AA1CYP2D6GRM5MAPK9MAPK14 | |
| SCHEMBL13910999 | 0.90 | HSP90AA1 (0.50) | HSP90AA1CYP2D6GRM5MAPK9MAPK14 | |
| SCHEMBL3107817 | 0.87 | LMNA (0.44) | HSP90AA1CYP2D6GRM5MAPK9MAPK14 | |
| SCHEMBL9903935 | 0.85 | CYP2D6 (0.60) | HSP90AA1CYP2D6GRM5MAPK9MAPK14 | |
| SCHEMBL4294864 | 0.84 | KDM4E (0.67) | HSP90AA1GRM5MAPK9MAPK14MAPK11 | |
| SCHEMBL29394083 | 0.84 | KDM4E (0.67) | HSP90AA1GRM5MAPK9MAPK14MAPK11 | |
| SCHEMBL25295479 | 0.83 | TP53 (0.48) | HSP90AA1CYP2D6GRM5MAPK9MAPK14 | |
| SCHEMBL5989213 | 0.83 | HSP90AA1 (0.44) | HSP90AA1CYP2D6GRM5MAPK9MAPK14 | |
| SCHEMBL8499115 | 0.83 | CYP2D6 (0.53) | HSP90AA1CYP2D6GRM5MAPK9MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710453-A | Kinase inhibitors and uses thereof | 璧辰医药技术股份有限公司 | 2023-09-05 | — | — | CN | disclosed |