SCHEMBL13042902

SCHEMBL13042902

C[Si](C)(C)O[Si](C)(CCC(CC(=O)O)CC(=O)O)O[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CACNA2D1 P54289 2/20 0.33
CACNB3 P54284 1/20 0.33
CACNA1C Q13936 1/20 0.33
PGR P06401 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
CACNA2D2 Q9NY47 1/20 0.33
GABRR1 P24046 2/20 0.30
LMNA P02545 1/20 0.30
SLC22A6 Q4U2R8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13042923 0.93 CACNA2D1 (0.30) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL13042868 0.85 CACNA2D1 (0.33) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL13042894 0.80 CACNA2D1 (0.31) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL13042911 0.80 CACNA2D1 (0.35) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL786839 0.75 FOLH1 (0.44) ADRA1A
SCHEMBL786925 0.74 CACNA2D1 (0.39) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL13042932 0.72 MMP12 (0.31)
SCHEMBL13042925 0.71 FOLH1 (0.40)
SCHEMBL14586576 0.70 CACNA2D1 (0.32) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL29728655 0.69 LMNA (0.42) LMNASLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8425803-B2 Nanocrystal doped matrixes SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-04-23 US disclosed
US-8283412-B2 Functionalized matrices for dispersion of nanostructures NANOSYS, INC. (US) 2012-10-09 US disclosed
US-20100276638-A1 Functionalized matrixes for dispersion of nanostructures NANOSYS, INC. (US) 2010-11-04 US disclosed
US-20100140551-A1 Nanocrystal doped matrixes NANOSYS, INC. (US) 2010-06-10 US disclosed
US-7645397-B2 Luminescent nanocomposite of luminescent nanocrystalline embedded in an epoxy, polyurea, or polyurethane matrix; retain luminescence; surfaces of nanocrystals having bound ligands comprising dicarboxylic acid moiety or aliphatic or polymeric amines; high efficiency solid-state white lighting; optics NANOSYS, INC. (US) 2010-01-12 US disclosed
US-20070034833-A1 Luminescent nanocomposite of luminescent nanocrystalline embedded in an epoxy, polyurea, or polyurethane matrix; retain luminescence; surfaces of nanocrystals having bound ligands comprising dicarboxylic acid moiety or aliphatic or polymeric amines; high efficiency solid-state white lighting; optics NANOSYS, INC. 2007-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100276638-A1 Functionalized matrixes for dispersion of nanostructures STRA6, EPHA6, MIF CACNA2D1 1976/4885CACNB3 3227/4885CACNA1C 3363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.