Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 5/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13107389 | 0.82 | CHAT (0.50) | CHATCHRNA7MAOBNFE2L2CYP19A1 | |
| SCHEMBL13030887 | 0.77 | CHAT (0.59) | CHATCHRNA7MAOBNFE2L2CYP19A1 | |
| SCHEMBL20614628 | 0.75 | CHAT (0.52) | CHATCHRNA7MAOBNFE2L2CYP19A1 | |
| SCHEMBL10615942 | 0.72 | KDM4A (0.57) | CHATMEN1KMT2AMAPT | |
| SCHEMBL10615946 | 0.72 | KDM4A (0.57) | CHATMEN1KMT2AMAPT | |
| SCHEMBL13030888 | 0.71 | CHAT (0.52) | CHATCHRNA7MEN1KMT2ARAB9A | |
| (Z)-1,2-Diphenylethene SCHEMBL9488275 | 0.71 | MAOB (0.73) | CHATMAOBNFE2L2CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL21847984 | 0.71 | MAOB (0.73) | CHATMAOBNFE2L2CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL347707 | 0.71 | MAOB (0.73) | CHATMAOBNFE2L2CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL22712863 | 0.71 | MAOB (0.73) | CHATMAOBNFE2L2CYP19A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7828858-B2 | Mixture of sulfide dyes | CIBA CORPORATION (US) | 2010-11-09 | — | — | US | disclosed |
| US-7811335-B2 | Hair dyes; deep dying; colorfast yet removable with an aqueous solution containing a reduction agent to disrupt the -S-S- bonds between the dye and the hair; quaternary pyridinium; disulfide; | CIBA SPECIALTY CHEMICALS CORP. (US) | 2010-10-12 | — | — | US | disclosed |
| US-20100000028-A1 | Styryl sulfide dyes | CIBA SPECIALTY CHEMICALS CORP. | 2010-01-07 | — | — | US | disclosed |
| US-20090100610-A1 | Mixture of Sulfide Dyes | CIBA CORPORATION | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090100610-A1 | Mixture of Sulfide Dyes | KRT18, TST, ARSA | CHAT 359/4885CHRNA7 3509/4885MAOB 1448/4885 |
| US-20100000028-A1 | Styryl sulfide dyes | C5, CBR3, C9 | CHAT 255/4885CHRNA7 851/4885MAOB 491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.