Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 7/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043665 | 0.80 | KDM4A (0.61) | RELAKDM4AKDM2AMEN1NPC1 | |
| SCHEMBL13030887 | 0.76 | CHAT (0.59) | CHATCHRNA7MEN1USP2RAB9A | |
| SCHEMBL10615942 | 0.76 | KDM4A (0.57) | CHATKDM4AKDM2AHTR2AMEN1 | |
| SCHEMBL10615946 | 0.76 | KDM4A (0.57) | CHATKDM4AKDM2AHTR2AMEN1 | |
| SCHEMBL20614628 | 0.75 | CHAT (0.52) | CHATCHRNA7MEN1USP2RAB9A | |
| SCHEMBL13201286 | 0.74 | MEN1 (0.42) | RELAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13107389 | 0.73 | CHAT (0.50) | CHATCHRNA7MEN1USP2RAB9A | |
| (Z)-1,2-Diphenylethene SCHEMBL5492329 | 0.72 | MAOB (0.58) | CHATRELATRPA1MEN1KMT2A | |
| Bromide SCHEMBL29216858 | 0.71 | CHAT (0.68) | CHATKDM4AKDM2AHTR2AMEN1 | |
| SCHEMBL13030896 | 0.71 | HTT (0.48) | ATMTAAR1MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100279340-A1 | Imaging agents for protein misfolding | NYU (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279340-A1 | Imaging agents for protein misfolding | APBA1, APP, SPG11 | CHAT 3608/4885CHRNA7 2437/4885ATM 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.