SCHEMBL13043576

SCHEMBL13043576

C=C/C=C(C)\C=C(/C)N(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.36
ALDH1A1 P00352 4/20 0.34
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
TRPM8 Q7Z2W7 2/20 0.33
POLB P06746 2/20 0.32
NPC1 O15118 2/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
FAAH O00519 1/20 0.32
PHGDH O43175 1/20 0.32
MGLL Q99685 1/20 0.32
TSHR P16473 1/20 0.31
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19443974 0.85 NPSR1 (0.41) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL24180823 0.84 ALDH1A1 (0.41) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL21085299 0.84 CYP3A4 (0.32) ALDH1A1KMT2AMEN1HPGDNPC1
SCHEMBL19867963 0.79 NPSR1 (0.36) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL18533863 0.76 NPSR1 (0.38) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL23519852 0.74 ALDH1A1 (0.36) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL18745271 0.72 NPSR1 (0.48) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL23116728 0.72 NPSR1 (0.40) NPSR1ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL23991849 0.72 FAAH (0.47) ALDH1A1KMT2AMEN1L3MBTL1POLB
SCHEMBL14535097 0.72 FAAH (0.47) ALDH1A1KMT2AMEN1L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2261270-A1 Polymer, producing method thereof, and photorefractive composition Nitto Denko Corporation (JP) 2010-12-15 EP disclosed