Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043652 | 0.87 | CNR1 (0.39) | RXRARXRBRXRGALDH1A1PTGDR2 | |
| SCHEMBL13044012 | 0.81 | THRA (0.42) | RXRARXRBRXRGPTGDR2SOAT1 | |
| SCHEMBL12646857 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGDBCL2L1HSD17B10CNR2 | |
| SCHEMBL27560312 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HPGDBCL2L1HSD17B10KDM4E | |
| SCHEMBL9713616 | 0.73 | ESR1 (0.46) | ALDH1A1PTGDR2CNR1CNR2KDM4E | |
| SCHEMBL27936087 | 0.73 | SOAT1 (0.49) | ALDH1A1HPGDBCL2L1HSD17B10CNR2 | |
| SCHEMBL13508915 | 0.72 | MGAM (0.39) | HPGDKDM4ELMNATDP1MEN1 | |
| SCHEMBL26612973 | 0.72 | ALDH1A1 (0.44) | ALDH1A1PTGDR2CNR1CNR2KDM4E | |
| SCHEMBL28897333 | 0.72 | SOAT1 (0.51) | ALDH1A1HPGDBCL2L1HSD17B10CNR2 | |
| 2-Phenylphenol SCHEMBL28343088 | 0.71 | ALDH1A1 (0.71) | ALDH1A1HPGDBCL2L1HSD17B10CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501840-B1 | BRIDGED BI-AROMATIC LIGANDS, COMPLEXES, CATALYSTS, PROCESSES FOR POLYMERIZING AND POLYMERS THEREFROM | SYMYX SOLUTIONS INC (US) | 2010-12-22 | — | — | EP | disclosed |
| US-7659415-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX SOLUTIONS, INC. (US) | 2010-02-09 | — | — | US | disclosed |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-7241715-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | WEE1, WASF2, WEE2 | RXRA 1054/4885RXRB 1381/4885RXRG 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.