Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044404 | 0.85 | THRA (0.39) | THRATHRBMEN1ALDH1A1POLB | |
| SCHEMBL13508907 | 0.79 | MAPT (0.40) | THRATHRBMEN1ALDH1A1KMT2A | |
| SCHEMBL13044012 | 0.77 | THRA (0.42) | THRATHRBRXRA | |
| SCHEMBL8242910 | 0.74 | THRA (0.47) | THRATHRBMEN1ALDH1A1POLB | |
| SCHEMBL6473245 | 0.73 | RXRA (0.46) | THRATHRBMEN1ALDH1A1POLB | |
| SCHEMBL29204862 | 0.72 | THRA (0.46) | THRATHRBMEN1ALDH1A1POLB | |
| SCHEMBL13144437 | 0.72 | THRA (0.46) | THRATHRBMEN1ALDH1A1POLB | |
| SCHEMBL13044014 | 0.70 | THRA (0.44) | THRATHRBMEN1ALDH1A1POLB | |
| SCHEMBL16687424 | 0.69 | THRA (0.47) | THRATHRBMEN1ALDH1A1POLB | |
| SCHEMBL6472679 | 0.69 | THRA (0.46) | THRATHRBMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501840-B1 | BRIDGED BI-AROMATIC LIGANDS, COMPLEXES, CATALYSTS, PROCESSES FOR POLYMERIZING AND POLYMERS THEREFROM | SYMYX SOLUTIONS INC (US) | 2010-12-22 | — | — | EP | disclosed |
| US-7659415-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX SOLUTIONS, INC. (US) | 2010-02-09 | — | — | US | disclosed |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-7241715-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | WEE1, WASF2, WEE2 | THRA 3478/4885THRB 3204/4885MEN1 4740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.