Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.52 |
| ▸ | HAT1 | O14929 | 2/20 | 0.51 |
| ▸ | EP300 | Q09472 | 2/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043225 | 0.88 | RAB9A (0.68) | NR4A2RAB9ANPC1CASP3SENP7 | |
| SCHEMBL13043513 | 0.87 | NR4A2 (0.60) | NR4A2RAB9ANPC1CASP3SENP7 | |
| SCHEMBL11924588 | 0.81 | RAB9A (0.76) | RAB9ANPC1CASP3SENP7IGF1R | |
| SCHEMBL13043222 | 0.81 | RAB9A (0.53) | NR4A2RAB9ANPC1CASP3SENP7 | |
| SCHEMBL13043227 | 0.78 | MAPT (0.52) | NR4A2RAB9ANPC1CASP3SENP7 | |
| SCHEMBL989756 | 0.78 | NR4A2 (0.73) | NR4A2RAB9ANPC1BRPF1HAT1 | |
| SCHEMBL28511881 | 0.77 | NR4A2 (0.65) | NR4A2RAB9ANPC1CASP3SENP7 | |
| SCHEMBL13044620 | 0.76 | RAB9A (0.62) | NR4A2RAB9ANPC1CASP3SENP7 | |
| SCHEMBL13044447 | 0.76 | RAB9A (0.65) | NR4A2RAB9ANPC1CASP3SENP7 | |
| SCHEMBL2036909 | 0.75 | NR4A2 (1.00) | NR4A2RAB9ANPC1BRPF1HAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |