Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043206 | 0.83 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL13043225 | 0.82 | RAB9A (0.68) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13044029 | 0.79 | NPC1 (0.56) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL13044442 | 0.78 | NR4A2 (0.59) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL13044596 | 0.75 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL13044632 | 0.75 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL22754851 | 0.74 | RAB9A (0.52) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL13044616 | 0.73 | RAB9A (0.68) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL13043185 | 0.73 | RAB9A (0.55) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL3805482 | 0.73 | RAB9A (0.67) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |