Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.45 |
| ▸ | TACR1 | P25103 | 4/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 4/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634225 | 0.86 | GHSR (0.67) | GHSRABCB1TACR1TACR3CCR3 | |
| SCHEMBL13044524 | 0.85 | GHSR (0.48) | GHSRABCB1MAPTALDH1A1KMT2A | |
| SCHEMBL3639856 | 0.85 | GHSR (0.52) | GHSRABCB1CCR3ALDH1A1KMT2A | |
| SCHEMBL3638183 | 0.84 | GHSR (0.71) | GHSRABCB1TACR1TACR3CCR3 | |
| SCHEMBL3639852 | 0.83 | GHSR (0.62) | GHSRABCB1TACR1TACR3KMT2A | |
| SCHEMBL13044526 | 0.83 | GHSR (0.61) | GHSRTACR1MAPTALDH1A1KMT2A | |
| SCHEMBL3636800 | 0.83 | GHSR (0.61) | GHSRTACR1MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL3638707 | 0.82 | GHSR (0.60) | GHSRTACR1MAPTALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL3636980 | 0.82 | GHSR (0.74) | GHSRABCB1TACR1TACR3 | |
| SCHEMBL3637124 | 0.82 | GHSR (0.68) | GHSRTACR1TACR3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GIPR, GHSR, GLP1R | GHSR 2/4885ABCB1 2178/4885TACR1 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.