Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.77 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.77 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.77 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | FYN | P06241 | 1/20 | 0.77 |
| ▸ | PGR | P06401 | 1/20 | 0.77 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.77 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.77 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.77 |
| ▸ | AR | P10275 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylstilbestrol SCHEMBL6542190 | 0.87 | ESR1 (1.00) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| Diethylstilbestrol SCHEMBL9223 | 0.87 | ESR1 (1.00) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| Diethylstilbestrol SCHEMBL27372002 | 0.87 | ESR1 (1.00) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| Diethylstilbestrol SCHEMBL9224 | 0.87 | ESR1 (1.00) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| Diethylstilbestrol SCHEMBL21351798 | 0.85 | ESR1 (0.95) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| Diethylstilbestrol SCHEMBL28317397 | 0.85 | ESR1 (0.95) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| Diethylstilbestrol SCHEMBL17594535 | 0.85 | ESR1 (0.95) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| Diethylstilbestrol SCHEMBL11333418 | 0.85 | ESR1 (0.95) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| Diethylstilbestrol SCHEMBL27619582 | 0.85 | ESR1 (0.95) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| Diethylstilbestrol SCHEMBL28180301 | 0.85 | ESR1 (0.95) | ESR1ESR2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141444-A1 | CHEMICALLY AMPLIFIED POSITIVE PHOTORESIST COMPOSITION | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2010-12-09 | — | — | WO | disclosed |