Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 6/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922573 | 0.83 | CFTR (0.51) | CFTRP2RY1TDP1FPR2SCN9A | |
| SCHEMBL11922609 | 0.83 | P2RY1 (0.46) | CFTRP2RY1TDP1ROCK2FPR2 | |
| SCHEMBL11922625 | 0.82 | P2RY1 (0.43) | CFTRP2RY1TDP1 | |
| SCHEMBL11991497 | 0.80 | P2RY1 (0.43) | CFTRP2RY1TDP1ROCK2FPR2 | |
| SCHEMBL7021224 | 0.80 | P2RY1 (0.43) | P2RY1MAPT | |
| SCHEMBL12303350 | 0.78 | P2RY1 (0.49) | P2RY1KDM4EROCK2MAPT | |
| SCHEMBL13044755 | 0.77 | CFTR (0.46) | CFTRKDM4EROCK2MAPT | |
| SCHEMBL11922628 | 0.75 | SCN9A (0.36) | CFTRP2RY1KDM4EROCK2FPR2 | |
| SCHEMBL22833380 | 0.75 | CFTR (0.66) | CFTRKDM4EMAPT | |
| SCHEMBL12303690 | 0.74 | TDP1 (0.49) | CFTRP2RY1TDP1FPR2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286131-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| US-20100286131-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| WO-2009018656-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286131-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2B | CFTR 1617/4885P2RY1 1931/4885KDM4E 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.