Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044808 | 0.95 | GAA (0.54) | GAACDK1TP53GLAMAPT | |
| SCHEMBL13328703 | 0.90 | GAA (0.40) | GAATP53MAPTPPARDMTNR1A | |
| SCHEMBL13328707 | 0.85 | GAA (0.41) | GAATP53MAPTPPARDMTNR1A | |
| SCHEMBL13044795 | 0.82 | GAA (0.55) | GAACDK1TP53GLAMAPT | |
| SCHEMBL3589040 | 0.77 | GAA (0.55) | GAACDK1TP53GLAMAPT | |
| SCHEMBL9699431 | 0.75 | GAA (0.50) | GAACDK1TP53GLAMAPT | |
| SCHEMBL9754517 | 0.74 | GAA (0.54) | GAACDK1TP53GLAMAPT | |
| SCHEMBL8855117 | 0.74 | GAA (0.51) | GAACDK1TP53GLAMAPT | |
| SCHEMBL3777329 | 0.73 | GAA (0.61) | GAACDK1TP53GLAMAPT | |
| SCHEMBL10801614 | 0.72 | SMN1; SMN2 (0.50) | GAACDK1TP53GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100285963-A1 | SUBSTITUTED FLUOROALKOXYPHENYLSULFONYLUREAS | MULLER KLAUS-HELMUT | 2010-11-11 | — | — | US | disclosed |
| US-20100285963-A1 | SUBSTITUTED FLUOROALKOXYPHENYLSULFONYLUREAS | MULLER KLAUS-HELMUT | 2010-11-11 | — | — | US | disclosed |
| US-20080076667-A1 | Substituted fluoroalkoxyphenylsulfonylureas | MULLER KLAUS-HELMUT | 2008-03-27 | — | — | US | disclosed |
| US-20080076667-A1 | Substituted fluoroalkoxyphenylsulfonylureas | MULLER KLAUS-HELMUT | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076667-A1 | Substituted fluoroalkoxyphenylsulfonylureas | PFAS, CBR3, CBR1 | GAA 872/4885CDK1 451/4885TP53 2426/4885 |
| US-20100285963-A1 | SUBSTITUTED FLUOROALKOXYPHENYLSULFONYLUREAS | PFAS, CBR3, CBR1 | GAA 872/4885CDK1 451/4885TP53 2426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.