Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14460614 | 0.98 | KMT2A (0.44) | MEN1KMT2AMCL1MAPTL3MBTL1 | |
| SCHEMBL14460615 | 0.96 | MEN1 (0.45) | MEN1KMT2AMCL1MAPTL3MBTL1 | |
| SCHEMBL14460242 | 0.89 | MEN1 (0.45) | MEN1KMT2AMAPTL3MBTL1HPGD | |
| SCHEMBL14460245 | 0.87 | KMT2A (0.41) | MEN1KMT2AMCL1MAPK1RXRA | |
| SCHEMBL14460232 | 0.87 | MEN1 (0.41) | MEN1KMT2AMCL1MAPK1RXRA | |
| SCHEMBL13043999 | 0.87 | MEN1 (0.38) | MEN1KMT2AMCL1MAPTRXRA | |
| SCHEMBL14460490 | 0.86 | MEN1 (0.47) | MEN1KMT2AMAPTL3MBTL1MAPK1 | |
| SCHEMBL14460231 | 0.85 | MEN1 (0.40) | MEN1KMT2AL3MBTL1MAPK1HPGD | |
| SCHEMBL14460318 | 0.85 | MEN1 (0.40) | MEN1KMT2AL3MBTL1MAPK1HPGD | |
| SCHEMBL14460268 | 0.85 | MEN1 (0.39) | MEN1KMT2AMCL1RXRATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689314-B2 | Methods for preparing bridged bi-aromatic ligands | UNIVATION TECHNOLOGIES, LLC (US) | 2020-06-23 | — | — | US | disclosed |
| EP-3632920-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | Univation Technologies, LLC (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-3286162-B1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | UNIVATION TECH LLC (US) | 2019-10-23 | — | — | EP | disclosed |
| US-10239809-B2 | Methods for preparing bridged bi-aromatic ligands | UNIVATION TECHNOLOGIES, LLC (US) | 2019-03-26 | — | — | US | disclosed |
| US-20180141883-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | UNIVATION TECHNOLOGIES, LLC (US) | 2018-05-24 | — | — | US | disclosed |
| US-20180141883-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | UNIVATION TECHNOLOGIES, LLC (US) | 2018-05-24 | — | — | US | disclosed |
| US-20180079704-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | UNIVATION TECHNOLOGIES, LLC (US) | 2018-03-22 | — | — | US | disclosed |
| US-20180079704-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | UNIVATION TECHNOLOGIES, LLC (US) | 2018-03-22 | — | — | US | disclosed |
| WO-2016172044-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | UNIVATION TECHNOLOGIES, LLC (US) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016172114-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | UNIVATION TECHNOLOGIES, LLC (US) | 2016-10-27 | — | — | WO | disclosed |
| EP-1501840-B1 | BRIDGED BI-AROMATIC LIGANDS, COMPLEXES, CATALYSTS, PROCESSES FOR POLYMERIZING AND POLYMERS THEREFROM | SYMYX SOLUTIONS INC (US) | 2010-12-22 | — | — | EP | disclosed |
| US-7659415-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX SOLUTIONS, INC. (US) | 2010-02-09 | — | — | US | disclosed |
| US-7659415-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX SOLUTIONS, INC. (US) | 2010-02-09 | — | — | US | disclosed |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-7241715-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241715-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079704-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | AOC1, TYR, DDT | MEN1 4381/4885KMT2A 2548/4885MCL1 1001/4885 |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | WEE1, WASF2, WEE2 | MEN1 4740/4885KMT2A 4545/4885MCL1 3690/4885 |
| US-10689314-B2 | Methods for preparing bridged bi-aromatic ligands | TYR, AOC2, BICRA | MEN1 4676/4885KMT2A 1799/4885MCL1 1076/4885 |
| US-10239809-B2 | Methods for preparing bridged bi-aromatic ligands | AOC1, TYR, DDT | MEN1 4381/4885KMT2A 2548/4885MCL1 1001/4885 |
| US-20180141883-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | TYR, AOC2, BICRA | MEN1 4676/4885KMT2A 1799/4885MCL1 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.