Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14184263 | 0.88 | ERBB2 (0.34) | NR1I2ERBB2CYP1A2FYNMAOA | |
| SCHEMBL13045236 | 0.79 | ALDH1A1 (0.44) | ERBB2CYP1A2FYNMAOAACHE | |
| SCHEMBL31717949 | 0.75 | NR1I2 (0.44) | NR1I2ERBB2CYP1A2FYNMAOA | |
| SCHEMBL244323 | 0.75 | ERBB2 (0.40) | ERBB2CYP1A2FYNMAOAACHE | |
| SCHEMBL13078791 | 0.74 | NPC1 (0.36) | — | |
| SCHEMBL4134538 | 0.74 | TSHR (0.38) | NR1I2ERBB2CYP1A2FYNMAOA | |
| SCHEMBL29773086 | 0.74 | CYP1A2 (0.36) | NR1I2ERBB2CYP1A2FYNMAOA | |
| SCHEMBL242040 | 0.74 | CYP1A2 (0.36) | NR1I2ERBB2CYP1A2FYNMAOA | |
| SCHEMBL12366101 | 0.74 | GRM2 (0.34) | — | |
| SCHEMBL28268583 | 0.73 | ALOX5AP (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833634-B2 | 1,8-naphthyridine compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2010-11-16 | — | — | US | disclosed |