Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28124903 | 0.88 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL14184251 | 0.85 | CYP1A2 (0.46) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL29986308 | 0.81 | AR (0.48) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL500184 | 0.81 | AR (0.48) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL30103752 | 0.80 | AR (0.47) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL12268955 | 0.80 | ADORA1 (0.37) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL2124728 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL29413360 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL29814212 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL13045234 | 0.79 | NR1I2 (0.32) | CYP1A2ERBB2FYNMAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833634-B2 | 1,8-naphthyridine compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2010-11-16 | — | — | US | disclosed |
| US-7833634-B2 | 1,8-naphthyridine compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2010-11-16 | — | — | US | disclosed |