SCHEMBL13045263

SCHEMBL13045263

CC1(C)c2ccccc2-c2ccc(-c3ccc(-c4cnc5ncc(-c6ccc(-c7ccc8c(c7)C(C)(C)c7ccccc7-8)cc6)cc5c4)cc3)cc21

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.39
PDK2 Q15119 17/20 0.39
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13045262 0.99 PDK2 (0.39) TDP2PDK2
SCHEMBL13045264 0.93 KDM4E (0.41) TDP2PDK2KDM4E
SCHEMBL14184257 0.85 PDK2 (0.40) TDP2PDK2
SCHEMBL81239 0.84 PDK2 (0.44) TDP2PDK2
SCHEMBL17324136 0.84 PDK2 (0.40) PDK2
SCHEMBL14184281 0.84 PDK2 (0.40) TDP2PDK2
SCHEMBL30009790 0.83 PDK2 (0.50) PDK2
SCHEMBL80381 0.82 PDK2 (0.45) PDK2
SCHEMBL80922 0.82 PDK2 (0.45) PDK2
SCHEMBL2965864 0.81 PDK2 (0.43) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7833634-B2 1,8-naphthyridine compound and organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2010-11-16 US disclosed
US-7833634-B2 1,8-naphthyridine compound and organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2010-11-16 US disclosed