SCHEMBL13045262

SCHEMBL13045262

CC1(C)c2ccccc2-c2ccc(-c3cnc4ncc(-c5ccc6c(c5)C(C)(C)c5ccccc5-6)cc4c3)cc21

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 17/20 0.39
TDP2 O95551 1/20 0.37
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13045263 0.99 TDP2 (0.39) PDK2TDP2
SCHEMBL13045264 0.91 KDM4E (0.41) PDK2TDP2
SCHEMBL17324136 0.85 PDK2 (0.40) PDK2ALOX5APFEN1
SCHEMBL14184281 0.85 PDK2 (0.40) PDK2TDP2
SCHEMBL80381 0.84 PDK2 (0.45) PDK2
SCHEMBL14184257 0.84 PDK2 (0.40) PDK2TDP2
SCHEMBL80922 0.84 PDK2 (0.45) PDK2
SCHEMBL2965864 0.82 PDK2 (0.43) PDK2
SCHEMBL81239 0.82 PDK2 (0.44) PDK2TDP2
SCHEMBL1649136 0.82 PDK2 (0.47) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140358198-A1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2014-12-04 US disclosed
US-20140358198-A1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2014-12-04 US disclosed
WO-2013087162-A1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2013-06-20 WO disclosed
US-7833634-B2 1,8-naphthyridine compound and organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2010-11-16 US disclosed
US-7833634-B2 1,8-naphthyridine compound and organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2010-11-16 US disclosed