Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13045263 | 0.93 | TDP2 (0.39) | KDM4ETDP2PDK2 | |
| SCHEMBL13045262 | 0.91 | PDK2 (0.39) | TDP2PDK2 | |
| SCHEMBL80774 | 0.87 | KDM4E (0.37) | KDM4ETDP2CLK4GSK3BDYRK1A | |
| SCHEMBL14184290 | 0.85 | SMN1; SMN2 (0.44) | TDP2PDGFRBPDGFRAPDK2MAP4K4 | |
| SCHEMBL12910375 | 0.80 | DAGLA (0.38) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL12910386 | 0.80 | KDM4E (0.36) | KDM4ETDP2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13388812 | 0.80 | HSD17B1 (0.46) | PDK2AXLCDK8CYP11B1CYP11B2 | |
| SCHEMBL22414232 | 0.80 | MEN1 (0.47) | KDM4ETDP2PDK2MAPT | |
| SCHEMBL13889562 | 0.80 | PDK2 (0.44) | KDM4ETDP2PDK2NPC1RAB9A | |
| SCHEMBL16716650 | 0.80 | MEN1 (0.47) | KDM4ETDP2PDK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833634-B2 | 1,8-naphthyridine compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2010-11-16 | — | — | US | disclosed |
| US-7833634-B2 | 1,8-naphthyridine compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2010-11-16 | — | — | US | disclosed |