Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899275 | 0.87 | KDM4E (0.45) | ALOX5NISCHKDM4EMGAMGAA | |
| SCHEMBL13045266 | 0.79 | CYP11B1 (0.54) | NISCHKDM4EPDGFRBPDGFRATOP2A | |
| SCHEMBL170247 | 0.75 | ALOX5 (0.62) | ALOX5ESR1ESR2NQO2CYP11B1 | |
| SCHEMBL29349888 | 0.75 | ALOX5 (0.62) | ALOX5ESR1ESR2NQO2CYP11B1 | |
| SCHEMBL28353300 | 0.75 | ALOX5 (0.62) | ALOX5NISCHESR1ESR2NQO2 | |
| SCHEMBL6684079 | 0.75 | ALOX5 (0.62) | ALOX5NISCHESR1ESR2NQO2 | |
| SCHEMBL13979072 | 0.74 | PDGFRB (0.50) | ALOX5NISCHKDM4EPDGFRBPDGFRA | |
| SCHEMBL27950152 | 0.74 | ALOX5 (0.59) | ALOX5NISCHKDM4EMGAMGAA | |
| SCHEMBL27916683 | 0.74 | ALOX5 (0.60) | ALOX5ESR1ESR2NQO2ALDH1A1 | |
| SCHEMBL13979068 | 0.73 | PDGFRB (0.53) | NISCHKDM4EPDGFRBPDGFRAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833634-B2 | 1,8-naphthyridine compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2010-11-16 | — | — | US | disclosed |
| US-7833634-B2 | 1,8-naphthyridine compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2010-11-16 | — | — | US | disclosed |