Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14184272 | 0.83 | CYP11B1 (0.56) | CYP11B1TRPM4PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL13706258 | 0.82 | CYP11B1 (0.51) | CYP11B1TRPM4PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL13045265 | 0.79 | ALOX5 (0.50) | CYP11B1PDGFRBPDGFRAALDH1A1HIF1A | |
| SCHEMBL13320308 | 0.78 | CYP11B1 (0.59) | CYP11B1TRPM4PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL16552261 | 0.77 | CYP11B1 (0.50) | CYP11B1TRPM4PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL13320296 | 0.76 | CYP11B1 (0.57) | CYP11B1TRPM4PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL12520821 | 0.75 | CYP11B1 (0.59) | CYP11B1TRPM4ALDH1A1HIF1AHSD17B10 | |
| SCHEMBL24910261 | 0.75 | NPC1 (0.52) | CYP11B1TRPM4PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL29832043 | 0.75 | NPC1 (0.52) | CYP11B1TRPM4PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL22170994 | 0.74 | CYP11B1 (0.50) | CYP11B1TRPM4PDGFRBPDGFRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833634-B2 | 1,8-naphthyridine compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2010-11-16 | — | — | US | disclosed |
| US-7833634-B2 | 1,8-naphthyridine compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2010-11-16 | — | — | US | disclosed |