Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532450 | 0.80 | PDGFRB (0.53) | KCNH2MAOAMAOBALDH1A1PDGFRB | |
| SCHEMBL6614214 | 0.73 | PDGFRB (0.50) | MAOAMAOBPDE10AALDH1A1PDGFRB | |
| SCHEMBL3396692 | 0.72 | CYP1A2 (0.55) | MAOAMAOBPDE10AALDH1A1HPGD | |
| SCHEMBL5037010 | 0.72 | MAOA (0.52) | MAOAMAOBTAAR1ALDH1A1CYP2A6 | |
| SCHEMBL14488614 | 0.72 | KDM4E (0.47) | KCNH2ALDH1A1HPGDALOX15TDP1 | |
| SCHEMBL23552159 | 0.71 | KCNH2 (0.36) | KCNH2PDE10APLAUTDP1 | |
| SCHEMBL9741303 | 0.71 | ALDH1A1 (0.69) | KCNH2MAOAMAOBTAAR1CA1 | |
| SCHEMBL62125 | 0.71 | ALDH1A1 (0.69) | KCNH2MAOAMAOBTAAR1CA1 | |
| SCHEMBL14184289 | 0.71 | TP53 (0.46) | KCNH2MAOAMAOBPDE10ATAAR1 | |
| Benzene SCHEMBL3440179 | 0.71 | ALDH1A1 (0.69) | KCNH2MAOAMAOBTAAR1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833634-B2 | 1,8-naphthyridine compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2010-11-16 | — | — | US | disclosed |